| Unicellular organism | Multicellular organism |
| 1. Body is made up of single cell | Body is made up of numerous cells |
| 2. Division of labour is at the organelle level. It gives a low level of operational efficiency | Division of labour may be at cellular, tissue, organ and organ system level. It gives high degree of operational efficiency |
| 3. A single cell carries out all the life processes | Different cells are specialized to perform different functions |
| 4. The cell body is exposed to the environment on all sides | Only outer cells are specialized to face the environment. Inner cells are devoted to other functions |
| 5. An injury of the cells can cause death of the organism. | Injury or death of some cells does not affect the organisms as the same can be replaced by new one. |
| 6. A cell body cannot attain a large size because of the limit imposed by surface area to volume ratio | A multicellular body can attain a large size increasing the number of small cells |
| 7. Lifespan is short due to heavy load of work | Lifespan is long due to limited load of work for each cell type |
| 8. Power of division is not lost | Certain specialized cells lose power of division |
| 9. A well-marked capacity of regeneration is present | The capacity of regeneration decreases with increasing specialization |
| 10. The cell has the same role for itself and the organism | Cells have a double role. One for themselves and other for the organism |
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